Tuesday, February 07, 2012

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Archive for the ‘Transfection Questions’ Category

Does anyone know of a good method for transfection of HEK 293 cells?

Question by Scooter: Does anyone know of a good method for transfection of HEK 293 cells?
I have been transfecting HEK 293 cells with Lipofectamine and I lose 90-100% of the cells after transfection. I’m trying to find a way to transfect and get the results I want with minimal cell death.

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Why does transfection efficiency increase when the amount of DNA added increases in cells?

Question by mjorizzle: Why does transfection efficiency increase when the amount of DNA added increases in cells?

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What is the proper technique to gain a stabily transfected cell line using Lipofectamine 2000 on HeLa cells?

Question by benji: What is the proper technique to gain a stabily transfected cell line using Lipofectamine 2000 on HeLa cells?
I know the general scheme, but wanted more specifics of how long to treat with reagent of choice and when to split when selecting.

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In vivo DNA transfection?

Question by Think.: In vivo DNA transfection?
Every time I hear about transfection, it refers to in vitro transfection. Is there any way to transfect DNA into cells in a living organism?

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