Posts Tagged ‘therapy’
Last Updated on Saturday, 10 July 2010 05:25 Written by Administrator Saturday, 10 July 2010 05:25
Research at the UW Medical Center translates to improving care options for patients. This University of Washington program shows what is going on in Dr. Clifford Hume,s lab, where researchers are exploring a biological approach to hearing restoration by stimulating regeneration of hair cells in the inner ear. To see more videos from the University of Washington visit uwtv.org.
Tags: Hearing, Loss, Molecular, therapy | Posted under Transfection Videos | 2 Comments
Last Updated on Wednesday, 7 July 2010 01:59 Written by Administrator Wednesday, 7 July 2010 01:59
Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) (Methods in Molecular Biology)
Oregon Health & Science Univ., Portland, OR. Text provides basic tools needed for design targeted gene delivery vectors, and an understanding of how to apply viral vectors to the treatment of genetic disorders. Includes step-by-step methods, vectors from major categories, guidance on the selection, and examples. DNLM: Genetic Vectors.
List Price: $ 159.00
Price: $ 34.94
Polyamine conjugates for non-viral gene therapy: polyamine conjugates for DNA and siRNA Transfection
Last Updated on Saturday, 5 June 2010 04:34 Written by Administrator Saturday, 5 June 2010 04:34
Polyamine conjugates for non-viral gene therapy: polyamine conjugates for DNA and siRNA Transfection
Polyamines Polyamines are naturally occurring small molecules and are found in high concentrations particularly in eukaryotic cells. Polyamines are often essentially fully protonated under physiological condition and these polycations also bind to DNA .Polyamines are present in chromatin and are believed to be involved in many cellular events and also to protect DNA from damage by free radicals. It is widely believed that gene therapy will become an efficient medicine for the treatment of diseases such as cancer, cystic fibrosis and for vaccination .The essential requirements for gene delivery are the transport of DNA through the cell membrane and ultimately to the nucleus. Different strategies have been used for the delivery of genetic material into target cells, classified as viral or non viral delivery systems. Efficient non viral formulation should be able to deliver safely the required DNA across the various cellular barriers to the nucleus.
List Price: $ 84.00
Price: $ 83.66
Tags: conjugates, gene, nonviral, Polyamine, siRNA, therapy, Transfection | Posted under Transfection Books | No Comments